Publications & References
Cell Line Genetics Publications
Evaluating the genomic and sequence integrity of human ES cell lines; comparison to normal genomes.
Stem Cell Res. 2012 Mar;8(2):154-64.
Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.
PLoS One. 2009 Oct 29. 4(10)
Protocols for cytogenetic studies of human embryonic stem cells
Methods. 2008 Jun;45(2):133-41.
Isolation and characterization of novel rhesus monkey embryonic stem cell lines.
Stem Cells. 2006 Oct;24(10):2177-86.
Customer Publications with CLG Collaboration
A pluripotent stem cell-based model for post-implantation human amniotic sac development.
Nat Commun. 2017 Aug;8(1):208.
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.
Nat Med. 2017 Jan;23(1):49-59.
Generation of stem cell-derived β-cells from patients with type 1 diabetes.
Nat Commun. 2016 May;10;7:11463.
Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications.
Stem Cell Rev and Rep (2016) 12: 394.
Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures.
DNA Res. 2015 Oct;22(5):331-42.
A comparison of non-integrating reprogramming methods.
Nature Biotechnology. 2015 Jan;33(1):58-63.
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells.
Nature. 2014 Mar 6;507(7490):99-103.
Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells.
Nature. 2014 Apr 28.
Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.
PLoS One. 2014 Apr 9;9(4)
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.
Cell. 2013 Dec 19;155(7):1479-91.
Somatic coding mutations in human induced pluripotent stem cells.
Nature. 2011 Mar 3;471(7336):63-7.
Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.
Cell. 2011 Jul 8;146(1):37-52.
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.
PLoS One. 2011;6(10)